World of Biochemistry

Gordon Research Conferences (GRC)

Developmental Biology is at the center of the Life Sciences. Developmental biologists discovered inductive tissue interactions, thus creating the field of cell-cell signaling. Developmental biologists have uncovered the basic biological processes of embryogenesis and pattern formation, organogenesis, neurogenesis and sex determination, aging and cell death, cell and tissue polarity, and epigenetics. Developmental biologists were the first to clone animals, revealing that adult nuclei contain all genetic information and setting up one of the major questions of biology – understanding the differential control of gene expression. Developmental biologists have discovered microRNAs and morphogens, defined and dissected the major signaling pathways, and uncovered fundamental principles of differential gene regulation. Developmental biologists have also provided important technological advances, from in situ hybridization and genome manipulation to in vivo imaging and RNAi. Developmental biologists have advanced our understanding of how organisms evolve (“EvoDevo”), have provided the foundations for stem cell biology and tissue engineering, have created the context to understand human birth defects and disease, and have started to provide a rich playing field for genomics and systems biology. The impact of the field is a result of the study of simple and complex whole organisms (rather than isolated cells or molecules) using a wide variety of technological and intellectual approaches. As these studies continue and expand into new areas such as regeneration, systems biology, and growth control, we can expect major contributions in the coming years. Hence, Developmental Biology has been and will continue to be a core discipline of the Life Sciences and is transforming the Medical Sciences.

The Gordon Research Conferences on Developmental Biology have been recognized for over thirty years as the preeminent mid-sized conferences for developmental biologists. The 5-day meeting will bring together ~150 outstanding senior and junior scientists for ~50 talks, ~80 posters and extensive discussions of the recent advances and future of the field. Speakers will cover classic topics and emerging areas in developmental biology: growth and patterning, stem cells and regeneration, axis formation, evolution, morphogenesis, signaling, organogenesis, and regulatory networks. In honor of the 40th anniversary of Lewis Wolpert’s Positional Information model, there will be a special session on Morphogen Gradients.